I don't use it much for that. I like Alexa's voice, so I do TTS differently using Google Assistant Relay and Samsung's cloud. However, of the times I've tried, it worked. YMMV on running the three together, but I'm not have a problem doing it. However, I don't ask much of the Chromecast Integration. It plays a door chime and tells cast web to shut up. So maybe when you don't do much with it, it doesn't cause problems?