Upgrading the firmware and the degradation of your Z-Wave mesh are likely coincidental. Most likely you have one or more devices that are unresponsive, whether they are going bad, or lingering "ghosts", or simply the hub is unable to communicate with them properly.
Running Z-Wave repair on an unhealthy mesh only furthers the problems, and may cause the entire mesh to go unresponsive. Identifying and addressing any and all devices that are unresponsive is the solution for your problem. As @thebearmay suggested, I would update the hub to the latest release, then methodically examine the Z-Wave nodes to ensure all are responsive. Once confirmed, then you could run a repair: Facts about Z-Wave Repair - #4 by bobbyD
If your problems persist, please send me a PM along with your hub's MAC address and I would be more than happy to check out your hub's engineering log to make sure that you are not dealing with a hardware malfunction.