Are these zigbee or zwave devices? And what are the distances to the hub? Reading your description it seems to me the devices are out of range or the radio network that they are on is either busy or not relaying the commands correctly.
Here are some options you could try (and check the logs whats happening then)
Zwave
Zwave Cleanup
http://hubitat.local/hub/zwave/nodeCleanup
Zwave Repair
http://hubitat.local/hub/zwaveRepair
Zigbee
https://docs2.hubitat.com/how-to/build-a-solid-zigbee-mesh
Zigbee Status
http://hubitat.local/hub/zigbee/getChildAndRouteInfo