I have a vacation mode on my alarm system. When this is activated, if the thermostat is set to heat, it drops the temp in the house to 55F, or if it's set to cool, it raises it to 79F. It shuts off all lights, locks all doors, etc.
When I was on Vera, I had a plugin called Deus ex Machina, and some other one that would basically create virtual "ghosts" that would haunt your house at night until a certain time turning lights on and off at random times to make it look like people were home. I haven't seen anything like this for HE yet.
Another thing that I haven't yet done is automate TV's turning on for some period of time. If I were a burglar and saw the light from a TV in a house or the TV itself, I would probably skip that house thinking someone was home.
I don't really do anything with the sensors connected directly to the HE for vacation, other than having the HE send me temp and water alert warnings (which are on all the time, not just vacation mode). My security system has plenty of sensors on its own to alert me of an intrusion.