Aside from totally disabling instead of pausing the rule, I'm not sure what else to suggest since it sounds like you've tried reasonable steps.
The trigger in rule 306 that you just posted is the only thing that seems like it might be a culprit. I think changes were made in 2.2.3 regarding how RM handles a single "any" trigger (or at least I know they were going to be made; not sure if it made this release). The problem it was intended to address is described in this thread. Perhaps it has some unintended consequences.
