I don't use Amazon/Echo but it looks the MS50A uses something that connects to Amazon.
The music playing can be controlled in the following ways:
(1) Touch panel on this speaker;
(2) Edifier Home App;
(3) Interactive voice devices: For Amazon Music, Spotify, Pandoura, Tuneln, iHeartRadio and other music services linked to Alexa, after relevant accounts are linked, you can play through Alexa and control this speaker by using other interactive voice devices like Echo.