Good question. However, I don't think "she" can, yet. You can set up a room in Alexa. This is usually, in my case at least, lights. You can add more, as many as you want but they will all be treated the same. "Alexa, turn on bedroom" results in everything in the room on. Not exactly what you want. You and I share the same goal. I have not found a way, yet. Now, I have the desired lights of each room set as the room with the Alexa device in that room. "Alexa, turn on the lights" results in the desired lights on in the room she and I are in. The fan? I have to name each a short simple one word name to help her differentiate which fan I want. Reading through the other replies, this seems to be the majority consensus. With the exception of "Nod Red" users. This may not be much help except to reassure you you are not alone, not missing anything and others have the same interest. Let's keep working on it.