This is primarily what I was following:
I didn't look too much into the official docs, I'll have to revisit that, as most of my interest has been in non-official integrations (like NodeRED)
All of my LR devices are 800 series. My media cabinet is right by a window, with direct line of sight to the devices. If it does have an issue, I can always move it closer, in the next few months I will be have two CAT6 runs out that way, if needed, I'll just move the Hubitat to within a few feet. I will make sure to try to provide as much info as I can on the LR devices, but my only real barrier for the signal is a triple paned window.
Let's say my hub and the devices were 15 feet away, would you set the z wave network up as mesh or star, knowing that I would never get beyond 50 devices.