Thought you were just asking about modes. Certainly changing scenes based on mode is possible. I have one scene for day (daylight white), one for evening (warm white), and one for night (dim nightlight). I set them based on mode via RM4. I use a virtual switch to determine whether automation should be turned on or off. The Motion Lighting app allows the use of a virtual switch to restrict automation as well. But, as I said, I’m not an expert. I can only describe what’s working for me.