Odd, something is definitely odd going on there, as I have 3 locks that I've not changed the batteries in since around April, and I have the Reliable Locks app polling every 5-10 minutes. I have one lock only that every once in a while is significantly delayed in firing a rule but after rebooting my hub usually clears that up.
I have noticed twice since I began using the Aeotecs that they appeared to stop working, which did cause locks to drop off, as in the green light no longer routinely blinks showing that it's communicating. After removing and repairing these went back to normal. Since then based on @aaiyar recommendation I've been using this driver for my repeaters as it sends a trace log every 30 minutes verifying the repeaters are "online" you might give this driver a shot also.
[RELEASE] Iris SmartPlug Z-Wave Repeater (3210-L + others)
