Hubitat will be fine. Dealing with the 2.4 ghz spectrum will be the key to that setup.
A few key points:
1:Make a spreadsheet to organize the bulbs, with each bulb document the location of the bulb, and the serial of that bulb -- ESPECIALLY if it's a pain in the ass to get to.
Hue has gotten significantly better when it comes to removing a bulb from one bridge and moving it to another, to the point where I haven't had to add a bulb by serial in a long time. However, you don't want to test this when that bulb which required a 15 foot ladder needs to be moved to a different bridge.
2: Move as many devices on your wifi network to 5 ghz if possible, and only use channels 6,11 with 20 mhz bands for any access points/routers that you have that will have 2.4 ghz broadcasting. You will most likely need to avoid using channel 1 (or 6 or 11, your choice) so that hubitat will have a open channel to use as it will broadcast throughout the house. Not to control your hue bulbs as that will be done over the LAN, but any other sensors that you are using
3: Do not centrally locate the bridges, locate the bridges with their group of lights and create "zones" for each bridge. You will need to re-use zigbee channels in the house to make this work, and the less interference the better. I'm assuming that this house has ethernet in every room, because if it doesn't it will be a giant pain in the ass to do this, and I would spend $8k on putting ethernet in every room before spending 8k on bulbs.
This is obviously a terrible 2D drawing of a house, but you will want something like this:
It's ok to have a couple bulbs on the edge of the wrong zone, but don't have a bulb that is connected to a bridge at the bottom right sitting at the top left in that image. That one bulb will wreck havoc will all the bulbs in the top left zone, while also not being responsive to the bridge that will need to control it.
4: Use a third party app that has the ability to create light groups. Huedynamic on windows/android/apple is a great one for this. Light groups are just a better version of "Rooms" that you can create with the native hue app -- They're better because you can share lights between groups, while rooms cannot.
Example for that monster setup, I would create a light group on every bridge that includes every lightbulb that the bridge controls and name it "EverythingZoneA", "EverythingZoneB", etc.
I would then create a virtual RGBW light bulb in hubitat, and have those 5 massive light groups mirror it. I would share the virtual RGBW bulb to Alexa and name it "Everything". You could then have your friend say "Alexa, turn off everything" and rather than it taking a minute for every light to turn off in the house, it would only take 3-5 seconds at most. If you have hue color bulbs everywhere you could turn the entire house red/blue/purple/etc in an instant. You could still share individual rooms to alexa as well, but the ability to quickly turn all light bulbs off in the house is useful and rather cool to see in person.
This is also a pretty good way of testing the zigbee mesh and finding bulbs that may perform better if shifted to a different zone, since there might be 1 light in the hallway that just doesn't turn off everytime when you tell it to.