Several of my z-wave switches and dimmers which normally never have issues are not responding. Rebooting the hub helps for a while but then the same devices eventually stop responding.
Currently running 2.1.4.130, both my zigbee and zwave have been solid.
No issues here on 2.1.4.130.
You may want to look at the guide for zwave for some useful zwave mesh information.
https://docs.hubitat.com/index.php?title=How_to_Build_a_Solid_Z-Wave_Mesh